nuvekta scientific · in development

Read every base.
Fold every idea.

Structure you can trust, from physics you can check.

A sequence platform for modern RNA biology. Read a transcript, fold its structure, and design against it on one continuous surface.

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Minimum free energyPartition functionBase-pair probabilities LinearFold · long sequencesModified bases · m1Ψ · inosineMelting temperature Primer & ASO designFASTA · GenBank · dot-bracket · CT Minimum free energyPartition functionBase-pair probabilities LinearFold · long sequencesModified bases · m1Ψ · inosineMelting temperature Primer & ASO designFASTA · GenBank · dot-bracket · CT
01 Import

A transcript, rendered base-by-base.

Drop in a sequence (FASTA, GenBank, or just paste it in) and see every base at native resolution. No tiling, no downsampling. The transcript becomes something you can actually hold and trust.

02 Annotate

Features and modified bases, layered in context.

Mark features, regions, and modified positions on one shared coordinate space. Click any base and see its context at once: its feature, its place inside a hairpin.

03 Fold

Secondary structure, straight from the engine.

Thermodynamic folding: minimum free energy and partition function. Hairpins draw themselves, and base-pair probabilities and ΔG come from an engine that holds its own against the field's standard tools.

04 Design

From sequence to oligo, without leaving the page.

Select a region, design primers and antisense oligos, and check Tm and structure on the same engine that folds. The transcript becomes a document you can author against.

The desktop app

One surface. Many tracks.
On your machine.

nuvekta runs natively on macOS today, with Windows and Linux to follow. Your sequences, structures, and annotations live on one surface, and it works offline. Built in React, TypeScript, and Tauri, with a custom canvas-and-SVG renderer.

nuvekta · synNGS-mRNA-Δ04
Tracks
Sequence
Features
Coverage
Variants 9
Annotations 8
Primers
Quality
Structure
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A stylized illustration of the workspace, not a screenshot. A real capture lands here as the app firms up.
Platform

Everything a sequence wants to be.

What works today, and what we're building next. We tag each one honestly, and never call something shipped before it is.

Sequence Viewer Live

Base-accurate rendering. Drag to select, click to annotate, jump anywhere. Multiple tracks sharing one coordinate space.

Structure Viewer Live

Secondary structure in 2D, with planar, circular, and linear layouts. Fold it, melt it by temperature, inspect any base. ΔG and base pairs come from the engine.

Design Studio In development

Primers, probes, guides, and oligos, with thermodynamics and secondary structure checked on the same engine that folds.

AI Model Development Planned

Learned models for RNA design and structure. An active research direction for us, trained and checked against the thermodynamic engine rather than replacing it.

Modified-Base Folding In development

Fold RNA with modified nucleotides like m1Ψ, pseudouridine, and inosine, the chemistry behind mRNA therapeutics and ADAR editing.

Batch & Scripting In development

Fold thousands of sequences in parallel from the command line, on the same engine that powers our benchmarks. Scriptable for your pipelines.

Melting & Temperature Live

Melting temperatures and melt curves from the partition function, so you can see how a structure opens as the temperature climbs.

Coverage Analytics Planned

Per-sample QC, dropout detection, cross-sample comparison. Click a dip in coverage to see the reads, click a read to see its entry.

Sequence Alignment Live

Align two sequences and compare them base by base, global (Needleman–Wunsch) or local (Smith–Waterman), with an identity score and a dot-plot view.

Early access

Want in early?

We're onboarding a small group of early users: RNA labs, oligo and mRNA teams, and anyone who lives in sequence files. Leave your email and we'll reach out as the platform opens up.

Thanks, you're on the list. We'll be in touch.
We'll only use your email to contact you about early access. See our privacy note.